Molecule of the Month May 2018 |
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Oxidation in the Catalytic Heart of the Ribosome: Differential Effects on Protein |
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Oxidative damage of biomolecules represents a serious threat to cell functions. Oxidation of non-coding RNAs with longer half-lives, such as tRNAs and rRNAs, represent a hazard for cell metabolism. Accumulating evidence links oxidized RNA to a variety of diseases, particularly age-related degeneration.
This work was carried out by Jessica Willi & colleagues in the group of Prof. Dr. Norbert Polacek and is the result of a collaboration between the Leumann & Polacek groups. References:
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