Molecule of the Month March 2019 |
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Targeting of the Mitochondrion by Dinuclear Thiolato-Bridged Arene Ruthenium Complexes in the Apicomplexan Parasite Neospora Caninum | ||
Dinuclear-thiolato bridged arene ruthenium complexes inhibit the apicomplexan N. caninum proliferation with low IC50 values of up to 1 nM, but do not affect human foreskin fibroblast (HFF) host cells at dosages of 5 µM and above.
This work was carried out in the group of Prof. Julien Furrer. References:
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