DNA-grafted supramolecular polymers combine the intrinsic properties of self-assembled materials with the potential of sequence-specific functionalization. R. Häner and co-workers describe the supramolecular polymerization of chimeric pyrene-DNA oligomers. The formation of helical ribbon structures is driven by pyrene stacking interactions and enables the controlled arrangement of oligonucleotide strands along the edges of the supramolecular polymers.

This work was carried out in the group of Prof. Robert Häner.

References:

• Y. Vyborna, M. Vybornyi, A.V. Rudnev, R. Häner;
  "DNA-Grafted Supramolecular Polymers: Helical Ribbon Structures Formed by Self-Assembly of Pyrene-DNA Chimeric Oligomers"
  Angew. Chem. Int. Ed., 54, 7719, (2015); doi:10.1002/anie.201504048   &
  Angew. Chem. Int. Ed., 54, 7934-7938, (2015); doi:10.1002/anie.201502066.